diff --git a/openssl-sys/build/expando.c b/openssl-sys/build/expando.c
index c8bfac879b081c84a569a93a273126a22e0c04fb..44a7b27f8956faf474c187ddec24df2bfffd90b4 100644
--- a/openssl-sys/build/expando.c
+++ b/openssl-sys/build/expando.c
@@ -10,10 +10,18 @@ VERSION(LIBRESSL, LIBRESSL_VERSION_NUMBER)
 VERSION(OPENSSL, OPENSSL_VERSION_NUMBER)
 #endif
 
+#ifdef OPENSSL_NO_BF
+RUST_CONF_OPENSSL_NO_BF
+#endif
+
 #ifdef OPENSSL_NO_BUF_FREELISTS
 RUST_CONF_OPENSSL_NO_BUF_FREELISTS
 #endif
 
+#ifdef OPENSSL_NO_CMS
+RUST_CONF_OPENSSL_NO_CMS
+#endif
+
 #ifdef OPENSSL_NO_COMP
 RUST_CONF_OPENSSL_NO_COMP
 #endif
@@ -46,6 +54,10 @@ RUST_CONF_OPENSSL_NO_PSK
 RUST_CONF_OPENSSL_NO_RFC3779
 #endif
 
+#ifdef OPENSSL_NO_RMD160
+RUST_CONF_OPENSSL_NO_RMD160
+#endif
+
 #ifdef OPENSSL_NO_SHA
 RUST_CONF_OPENSSL_NO_SHA
 #endif
diff --git a/openssl/src/hash.rs b/openssl/src/hash.rs
index 1136b6b1489f3197cd68028641ce5e0a5f002e1a..4f8fe3762d1f929e043b8c4475efee4709633add 100644
--- a/openssl/src/hash.rs
+++ b/openssl/src/hash.rs
@@ -104,6 +104,7 @@ impl MessageDigest {
         unsafe { MessageDigest(ffi::EVP_shake256()) }
     }
 
+    #[cfg(not(osslconf = "OPENSSL_NO_RMD160"))]
     pub fn ripemd160() -> MessageDigest {
         unsafe { MessageDigest(ffi::EVP_ripemd160()) }
     }
diff --git a/openssl/src/lib.rs b/openssl/src/lib.rs
index b4e647c0768b489da2b8500f36c16ec3259cd78f..07ec23c95c5419f76168bd8ac427d2dcb351cc62 100644
--- a/openssl/src/lib.rs
+++ b/openssl/src/lib.rs
@@ -143,7 +143,7 @@ pub mod aes;
 pub mod asn1;
 pub mod base64;
 pub mod bn;
-#[cfg(not(libressl))]
+#[cfg(all(not(libressl), not(osslconf = "OPENSSL_NO_CMS")))]
 pub mod cms;
 pub mod conf;
 pub mod derive;
diff --git a/openssl/src/symm.rs b/openssl/src/symm.rs
index 45c5dd9b3d61439783d9d9e0ce035cd08969aa94..beea446b583e1688a373c96e7463cfde04d743f8 100644
--- a/openssl/src/symm.rs
+++ b/openssl/src/symm.rs
@@ -224,18 +224,22 @@ impl Cipher {
         unsafe { Cipher(ffi::EVP_aes_256_ocb()) }
     }
 
+    #[cfg(not(osslconf = "OPENSSL_NO_BF"))]
     pub fn bf_cbc() -> Cipher {
         unsafe { Cipher(ffi::EVP_bf_cbc()) }
     }
 
+    #[cfg(not(osslconf = "OPENSSL_NO_BF"))]
     pub fn bf_ecb() -> Cipher {
         unsafe { Cipher(ffi::EVP_bf_ecb()) }
     }
 
+    #[cfg(not(osslconf = "OPENSSL_NO_BF"))]
     pub fn bf_cfb64() -> Cipher {
         unsafe { Cipher(ffi::EVP_bf_cfb64()) }
     }
 
+    #[cfg(not(osslconf = "OPENSSL_NO_BF"))]
     pub fn bf_ofb() -> Cipher {
         unsafe { Cipher(ffi::EVP_bf_ofb()) }
     }